{"id":10793,"date":"2022-07-20T09:06:02","date_gmt":"2022-07-20T09:06:02","guid":{"rendered":"https:\/\/haberulus.net\/?p=10793"},"modified":"2022-07-20T09:06:02","modified_gmt":"2022-07-20T09:06:02","slug":"depresyon-ve-dusuk-serotonin-duzeyi-arasinda-baglanti-bulunamadi","status":"publish","type":"post","link":"https:\/\/haberulus.net\/?p=10793","title":{"rendered":"Depresyon ve d\u00fc\u015f\u00fck serotonin d\u00fczeyi aras\u0131nda ba\u011flant\u0131 bulunamad\u0131"},"content":{"rendered":"

Depresyonla ilgili bir ara\u015ft\u0131rma bilim d\u00fcnyas\u0131nda yeni sorular\u0131 g\u00fcndeme getirdi. \u00c7al\u0131\u015fmada d\u00fc\u015f\u00fck serotonin seviyesi ile depresyon aras\u0131nda herhangi bir kan\u0131t bulunamamas\u0131 antidepresanlara kar\u015f\u0131 artan ba\u011f\u0131ml\u0131l\u0131\u011f\u0131 da sorgulad\u0131.<\/b><\/p>\n

University College London ara\u015ft\u0131rmac\u0131lar\u0131, depresyonun kimyasal bir dengesizlikten kaynakland\u0131\u011f\u0131na dair ikna edici kan\u0131t olmad\u0131\u011f\u0131n\u0131 savunuyorlar.<\/p>\n

Ara\u015ft\u0131rmaya kat\u0131lan bir akademisyen, \u201cbildi\u011fimi sand\u0131\u011f\u0131m her \u015fey alt \u00fcst oldu\u201d dedi.<\/p>\n

Ara\u015ft\u0131rman\u0131n ba\u015f yazar\u0131 Profes\u00f6r Joanna Moncrieff \u015funlar\u0131 s\u00f6yledi: \u201cKimyasal dengesizlik teorisinin pop\u00fclaritesi, antidepresan kullan\u0131m\u0131nda b\u00fcy\u00fck bir art\u0131\u015fla ayn\u0131 zamana denk geldi. Binlerce ki\u015fi, antidepresanlar\u0131n yan etkilerine maruz kald\u0131, ancak re\u00e7eteler artmaya devam etti. Bu durumun depresyonun kimyasal bir dengesizlikten kaynakland\u0131\u011f\u0131na dair yanl\u0131\u015f inan\u00e7tan kaynakland\u0131\u011f\u0131na inan\u0131yoruz. Bu inanc\u0131n bilime dayanmad\u0131\u011f\u0131n\u0131 kamuoyuna bildirmenin zaman\u0131 geldi.\u201d<\/p>\n

SEROTON\u0130N \u0130LE \u0130LG\u0130L\u0130 OLD\u011eUNA DA\u0130R KANIT YOK<\/b><\/p>\n

Molecular Psychiatry dergisinde yay\u0131nlanan UCL \u00e7al\u0131\u015fmas\u0131, 2010 y\u0131l\u0131na dayanan ve \u00f6nceki 17 incelemeyi analiz etti. \u00c7al\u0131\u015fma, SSRI\u2019lar\u0131n \u00e7al\u0131\u015fmad\u0131\u011f\u0131n\u0131 kan\u0131tlamad\u0131\u011f\u0131n\u0131 ancak ila\u00e7lar\u0131n anormal derecede d\u00fc\u015f\u00fck serotonin seviyelerini sabitleyerek depresyonu tedavi etmedi\u011fini de \u00f6ne s\u00fcr\u00fcyor.<\/p>\n

\"\"<\/p>\n

Profes\u00f6r Moncrieff, \u201cOn y\u0131llar boyunca y\u00fcr\u00fct\u00fclen \u00e7ok say\u0131da ara\u015ft\u0131rmadan sonra, depresyonun serotonin anormalliklerinden, \u00f6zellikle daha d\u00fc\u015f\u00fck seviyelerde veya serotonin aktivitesinin azalmas\u0131ndan kaynakland\u0131\u011f\u0131na dair ikna edici bir kan\u0131t olmad\u0131\u011f\u0131n\u0131 g\u00fcvenle s\u00f6yleyebiliriz.\u201d<\/p>\n

ETK\u0130LER\u0130 YOK AMA KULLANIMLARI ARTIYOR<\/b><\/p>\n

Rakamlara g\u00f6re alt\u0131 \u0130ngiliz yeti\u015fkinden biri ve Amerikal\u0131lar\u0131n yakla\u015f\u0131k y\u00fczde 13\u2019\u00fc antidepresan kullan\u0131yor.<\/p>\n

\u0130ngiltere Ulusal Sa\u011fl\u0131k Sistemi\u00a0verileri, 2021\/22\u2019de bir \u00f6nceki y\u0131la g\u00f6re y\u00fczde 6 daha fazla olan 8,3 milyon hasta ile \u0130ngiltere\u2019de verilen re\u00e7etelerde bir art\u0131\u015f oldu\u011funu g\u00f6steriyor.<\/p>\n

\u0130la\u00e7lardan en yayg\u0131n olanlar\u0131 ise Prozac, Cipramil ve Lustral gibi SSRI\u2019lar. Daha az yan etkiye neden olduklar\u0131 i\u00e7in di\u011fer antidepresan t\u00fcrlerine tercih edilirler. Yine de kayg\u0131, ishal, ba\u015f d\u00f6nmesi ve bulan\u0131k g\u00f6rme gibi yan etkilere neden olurlar.<\/p>\n","protected":false},"excerpt":{"rendered":"

Depresyonla ilgili bir ara\u015ft\u0131rma bilim d\u00fcnyas\u0131nda yeni sorular\u0131 g\u00fcndeme getirdi. \u00c7al\u0131\u015fmada d\u00fc\u015f\u00fck serotonin seviyesi ile depresyon aras\u0131nda …<\/p>\n","protected":false},"author":1,"featured_media":10794,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[3116,226,3115,3117,3118],"class_list":["post-10793","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-antidepresan","tag-arastirma","tag-depresyon","tag-kanit","tag-serotonin"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/10793","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10793"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/10793\/revisions"}],"predecessor-version":[{"id":10795,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/10793\/revisions\/10795"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/10794"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10793"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10793"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10793"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}