\u0130nsanlarda X ve Y olmak \u00fczere iki cinsiyet kromozomu vard\u0131r. Erkeklerde tipik olarak bir X bir Y bulunurken, kad\u0131nlarda iki adet X kromozomu bulunur.<\/span><\/p>\n Bununla birlikte, bilim insanlar\u0131, Y kromozomunun kayb\u0131n\u0131n do\u011frudan hastal\u0131\u011fa neden olup olmad\u0131\u011f\u0131n\u0131 veya k\u0131r\u0131\u015f\u0131kl\u0131klar veya grile\u015fen sa\u00e7lar gibi, sadece bir ya\u015flanma belirtisi olup olmad\u0131\u011f\u0131n\u0131 belirleyemediler.<\/span><\/p>\n \u015eimdi, Daily Mail\u2019in haberine g\u00f6re,\u00a0bilim insanlar\u0131 ilk kez Y kromozomu kayb\u0131n\u0131n kalbe zarar verebilece\u011fini g\u00f6sterdiler.<\/span><\/p>\n FARELERDE VE \u0130NSANLARDA \u0130NCELEND\u0130<\/b><\/p>\n ABD\u2019deki Virginia \u00dcniversitesi ve \u0130sve\u00e7\u2019teki Uppsala \u00dcniversitesi\u2019nden bilim insanlar\u0131, ba\u011flant\u0131y\u0131 ilk olarak farelerde kan\u0131tlad\u0131lar.<\/span><\/p>\n Beyaz kan h\u00fccrelerinden Y-kromozomu olmayan farelerin, hala Y-kromozomlar\u0131na sahip olan farelerden daha erken \u00f6ld\u00fcklerini g\u00f6sterdiler.<\/span><\/p>\n Y kromozomu d\u00fc\u015f\u00fck olan farelerde ayr\u0131ca kalp kaslar\u0131nda daha fazla fibroz veya kal\u0131nla\u015fma geli\u015fti. Bu kal\u0131nla\u015fma kalbi sertle\u015ftirir ve kan pompalamas\u0131n\u0131 zorla\u015ft\u0131r\u0131r.<\/span><\/p>\n Ara\u015ft\u0131rmac\u0131lar daha sonra insanlara ge\u00e7ti ve b\u00fcy\u00fck bir sa\u011fl\u0131k veri taban\u0131 olan UK Biobank\u2019a kan \u00f6rnekleri veren 223.000\u2019den fazla erke\u011fe ili\u015fkin t\u0131bbi ve genetik bilgilere bakt\u0131lar.<\/span><\/p>\n Beyaz kan h\u00fccrelerinin y\u00fczde 40\u2019\u0131ndan fazlas\u0131ndan Y kromozomlar\u0131n\u0131 kaybeden erkeklerin, sonraki 12 y\u0131l i\u00e7inde, kalp yetmezli\u011fi de dahil olmak \u00fczere kalp rahats\u0131zl\u0131klar\u0131ndan \u00f6lme olas\u0131l\u0131\u011f\u0131n\u0131n, olmayanlara g\u00f6re y\u00fczde 31 daha fazla oldu\u011funu buldular.<\/span><\/p>\n Ara\u015ft\u0131rmac\u0131lar, Y kayb\u0131n\u0131n; kalp kas\u0131 fibrozisine, kalp fonksiyon bozuklu\u011funa ve erkeklerde \u00f6l\u00fcme katk\u0131da bulundu\u011funu g\u00f6sterdi\u011fi sonucuna vard\u0131lar.<\/span><\/p>\n Y kromozomunun kayb\u0131n\u0131n kalpteki baz\u0131 h\u00fccrelerin \u00e7al\u0131\u015fmas\u0131n\u0131 etkileyerek fibrozis ve kalp hastal\u0131\u011f\u0131na neden oldu\u011funu d\u00fc\u015f\u00fcn\u00fcyorlar.<\/span><\/p>\n \u00a0<\/p>\n \u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":" Yeni ara\u015ft\u0131rmalara g\u00f6re, insan DNA’s\u0131n\u0131n erkeklere \u00f6zg\u00fc par\u00e7as\u0131 olan Y kromozomunun ya\u015fa ba\u011fl\u0131 kayb\u0131, erkeklerin ya\u015fland\u0131k\u00e7a potansiyel olarak …<\/p>\n","protected":false},"author":1,"featured_media":14566,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[500,3932,169,1012,3933],"class_list":["post-14565","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-insan","tag-kalp","tag-kan","tag-kaybi","tag-y-kromozomu"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/14565","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14565"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/14565\/revisions"}],"predecessor-version":[{"id":14567,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/14565\/revisions\/14567"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/14566"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14565"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14565"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14565"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"https:\/\/i01.sozcucdn.com\/wp-content\/uploads\/2022\/07\/26\/shutterstock_1723725676-1-660x440.jpg\" "\\"\\"")
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