{"id":16914,"date":"2022-07-31T03:06:03","date_gmt":"2022-07-31T03:06:03","guid":{"rendered":"https:\/\/haberulus.net\/?p=16914"},"modified":"2022-07-31T03:06:03","modified_gmt":"2022-07-31T03:06:03","slug":"urik-asit-yuksekligine-dikkat","status":"publish","type":"post","link":"https:\/\/haberulus.net\/?p=16914","title":{"rendered":"\u00dcrik asit y\u00fcksekli\u011fine dikkat!"},"content":{"rendered":"

\u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 Prof. Dr. Osman Erk, \u201c\u00dcrik asit y\u00fcksekli\u011fi; karaci\u011fer ya\u011flanmas\u0131 ve hipertansiyona yol a\u00e7t\u0131\u011f\u0131 gibi kalp damar hastal\u0131klar\u0131 riskini de artt\u0131rmaktad\u0131r\u201d dedi ve dikkat edilmesi gerekenleri s\u0131ralad\u0131.<\/b><\/p>\n

Kanda \u00fcrik asit fazlal\u0131\u011f\u0131 (hiper\u00fcrisemi) ya fazla \u00fcrik asit yap\u0131m\u0131 ya \u00fcrik asidin v\u00fccuttan at\u0131lmas\u0131nda azalma ya da bu iki mekanizman\u0131n bir arada i\u015flemesi sonucu ortaya \u00e7\u0131kar. Yani \u00fcrik asit yap\u0131m\u0131 artm\u0131\u015ft\u0131r ve\/veya at\u0131l\u0131m\u0131 azalm\u0131\u015ft\u0131r. \u00dcrik asidin b\u00fcy\u00fck bir k\u0131sm\u0131 b\u00f6brekler taraf\u0131ndan, daha az bir k\u0131sm\u0131 ise ba\u011f\u0131rsaklar yolu ile elimine edilmektedir. \u015eeker hastal\u0131\u011f\u0131, hipertansiyon ve \u00fcrik asit y\u00fcksekli\u011fi karde\u015f hastal\u0131klard\u0131r. Biri ortaya \u00e7\u0131kt\u0131\u011f\u0131 zaman di\u011ferinin de ortaya \u00e7\u0131kma ihtimali y\u00fcksektir. \u00dcrik asit y\u00fcksekli\u011fi ayn\u0131 zamanda metabolik sendrom olarak ifade edilen bir hastal\u0131k durumunun da unsurlar\u0131ndan biridir. Metabolik sendromda abdominal obezite (bel kal\u0131nl\u0131\u011f\u0131), \u015feker hastal\u0131\u011f\u0131, hipertansiyon, kanda HDL’nin d\u00fc\u015f\u00fckl\u00fc\u011f\u00fc ve trigliseridlerin y\u00fcksekli\u011fi bir arada g\u00f6r\u00fclmektedir. Bu tablo i\u00e7inde \u00fcrik asit y\u00fcksekli\u011fi; karaci\u011fer ya\u011flanmas\u0131 ve hipertansiyona yol a\u00e7t\u0131\u011f\u0131 gibi, kalp damar hastal\u0131klar\u0131 riskini de artt\u0131rmaktad\u0131r. Proteinli g\u0131dalar\u0131n v\u00fccutta ins\u00fclin art\u0131\u015f\u0131na neden oldu\u011fu bilinmektedir.<\/p>\n

\"\"<\/p>\n

Prof. Dr. Osman Erk<\/p>\n<\/div>\n

Fruktoz \u00fcrik asidi y\u00fckseltir<\/b><\/p>\n

Fazla miktarda fruktoz ayn\u0131 zamanda karaci\u011fer ya\u011flanmas\u0131 ve ins\u00fclin direncine neden olur ve \u00fcrik asit y\u00fckselir. Bu nedenle g\u00fcnl\u00fck fruktoz al\u0131m\u0131n\u0131 50 gram ile s\u0131n\u0131rlamak ve m\u00fcmk\u00fcnse bunu g\u00fcn boyuna yaymak uygun olacakt\u0131r. G\u00fcnde 50 gramdan fazla fruktoz al\u0131m\u0131n\u0131n karaci\u011fere toksik oldu\u011fu; karaci\u011feri ya\u011fland\u0131rd\u0131\u011f\u0131; \u00fcrik asit art\u0131\u015f\u0131na neden oldu\u011fu; metabolik sendrom riskini, diyabet ve kalp damar hastal\u0131klar\u0131 riskini artt\u0131rd\u0131\u011f\u0131 anla\u015f\u0131lm\u0131\u015ft\u0131r. Meyvelerde bulunan C vitamini, folik asit ve antioksidanlar \u00fcrik asidin b\u00f6brekler yolu ile at\u0131l\u0131m\u0131n\u0131 h\u0131zland\u0131rarak \u00fcrik asit y\u00fcksekli\u011fini s\u0131n\u0131rland\u0131rmaktad\u0131r. \u0130\u00e7inde C vitamini, folik asit, lif bulunmayan meyve sular\u0131 ve gazl\u0131 i\u00e7eceklerin \u00fcrik asidi y\u00fckseltme potansiyelleri olduk\u00e7a fazlad\u0131r.<\/p>\n

\"\"<\/p>\n

Meyveler ve bal<\/b><\/p>\n

Meyve ve balda fruktoz miktar\u0131 fazlad\u0131r, bu nedenle \u00fcrik asit olu\u015fumu artar. Fakat meyve ve balda bulunan C vitamini, di\u011fer vitaminler ve antioksidanlar, olu\u015fan \u00fcrik asidin b\u00f6brekler yoluyla at\u0131lmas\u0131n\u0131 artt\u0131rarak dengeyi sa\u011flarlar. \u00d6zellikle C vitamini \u00fcrik asit at\u0131l\u0131m\u0131n\u0131 te\u015fvik eden \u00f6nemli bir antioksidan vitamindir. Meyve sular\u0131nda C vitamini miktar\u0131 \u00e7ok d\u00fc\u015f\u00fck oldu\u011fu i\u00e7in ve lif i\u00e7ermedikleri i\u00e7in \u00fcrik asit y\u00fckselebilir. Hayvansal a\u011f\u0131rl\u0131kl\u0131 beslenenlerde hem \u00fcrik asit olu\u015fumu artt\u0131\u011f\u0131 i\u00e7in, hem de C vitamini olmad\u0131\u011f\u0131ndan dolay\u0131 \u00fcrik asit at\u0131l\u0131m\u0131 azald\u0131\u011f\u0131 i\u00e7in gut krizleri artabilir.<\/p>\n

\"\"<\/p>\n

\u00a0<\/p>\n

Tansiyon ila\u00e7lar\u0131<\/b><\/p>\n

Hipertansiyon olduk\u00e7a s\u0131k bir hastal\u0131kt\u0131r. T\u00fcm d\u00fcnyada bir milyardan fazla hipertansiyon hastas\u0131 vard\u0131r ve bizim toplumumuzda da hipertansiyon s\u0131kl\u0131\u011f\u0131 %30-35 d\u00fczeyindedir. Hipertansiyon tedavisinde s\u0131k olarak kullan\u0131lan tiazid grubu idrar s\u00f6kt\u00fcr\u00fcc\u00fcler \u015feker d\u00fczeyini olumsuz etkilerler ve \u00fcrik asit d\u00fczeyini y\u00fckseltirler. Sadece bu nedenle ki\u015fide metabolik sendrom ortaya \u00e7\u0131kabilir. Metabolik sendromda tansiyonun daha da y\u00fckseldi\u011fi bilinmektedir. Bu t\u00fcr ila\u00e7lar hipertansiyon tedavisinde m\u00fcmk\u00fcn oldu\u011fu kadar az kullan\u0131lmal\u0131d\u0131r. Yine g\u00fcndelik hayatta s\u0131k olarak kullan\u0131lan aspirin, \u00fcrik asidin b\u00f6breklerle at\u0131l\u0131m\u0131n\u0131 zorla\u015ft\u0131rarak \u00fcrik asit d\u00fczeyini y\u00fckselte biliyor.<\/p>\n

Gut nas\u0131l ortaya \u00e7\u0131kar? Belirtileri nelerdir?<\/b><\/p>\n

Gut, sodyum \u00fcrat kristallerinin eklemlerde birikmesine ve \u00e7\u00f6kmesine ba\u011fl\u0131 olarak ortaya \u00e7\u0131kan bir eklem yang\u0131s\u0131 durumudur. Genellikle fazla protein ve alkol i\u00e7eren bir yemek sonras\u0131, gece sabaha kar\u015f\u0131 ortaya \u00e7\u0131kar. Erkeklerde s\u0131kt\u0131r. Gutun ilk ve en \u00f6nemli belirtisi \u00e7ok a\u011fr\u0131l\u0131, akut ba\u015flang\u0131\u00e7l\u0131 bir eklem krizidir. En s\u0131k ayak ba\u015fparma\u011f\u0131nda ortaya \u00e7\u0131kar. Ayak ba\u015fparma\u011f\u0131 son derece a\u011fr\u0131l\u0131, \u015fi\u015f ve k\u0131zar\u0131kt\u0131r; elle dokunuldu\u011funda bile m\u00fcthi\u015f a\u011fr\u0131 vard\u0131r. Ayak ba\u015fparma\u011f\u0131 d\u0131\u015f\u0131nda aya\u011f\u0131n di\u011fer eklemleri, diz, el bile\u011fi, el parmak eklemleri ve dizlerde akut atak ortaya \u00e7\u0131kabilir. Ataklar; \u00f6nceleri tek bir eklemde ortaya \u00e7\u0131karken, ilerleyen zamanlarda birden fazla eklemi tutma olas\u0131l\u0131\u011f\u0131 artar. Her \u00fcrik asit y\u00fckseldi\u011finde gut ata\u011f\u0131 ortaya \u00e7\u0131kmaz fakat gut hastal\u0131\u011f\u0131 genellikle \u00fcrik asit y\u00fcksekli\u011finden sonra ortaya \u00e7\u0131kar.<\/p>\n

Gut hastal\u0131\u011f\u0131 risk fakt\u00f6rleri<\/b><\/p>\n

\u25a0 Diyet<\/p>\n

\u25a0Hareketsiz ya\u015fam<\/p>\n

\u25a0 \u015ei\u015fmanl\u0131k ve metabolik sendrom<\/p>\n

\u25a0 Hipertansiyon<\/p>\n

\u25a0 Diyabet<\/p>\n

\u25a0 Kalp yetersizli\u011fi<\/p>\n

\u25a0 Kronik b\u00f6brek yetersizli\u011fi<\/p>\n

\u25a0 \u0130drar s\u00f6kt\u00fcr\u00fcc\u00fc ve aspirin kullan\u0131m\u0131<\/p>\n

\u25a0 Kanser<\/p>\n

Alkol gut krizini kolayla\u015ft\u0131r\u0131r<\/b><\/p>\n

Alkol, hem \u00fcrik asit yap\u0131m\u0131n\u0131 artt\u0131rarak hem de \u00fcrik asit at\u0131l\u0131m\u0131n\u0131 azaltarak \u00fcrik asit y\u00fcksekli\u011fine yol a\u00e7ar. Bira fazla miktarda p\u00fcrin i\u00e7ermektedir ve risklidir. Alkol\u00fcn cinsinden \u00e7ok miktar\u0131 \u00f6nemlidir. G\u00fcnde 15 gramdan fazla alkol (\u015farap, bira ve di\u011ferleri) hiper\u00fcrisemi riskini y\u00fczde 90 artt\u0131r\u0131r.<\/p>\n

Nelere dikkat edilmeli?<\/b><\/p>\n

\u25a0 \u00dcrik asit y\u00fcksekli\u011fi metabolik bir hastal\u0131k olarak kabul edilmeli, kalori k\u0131s\u0131tlanmas\u0131 yap\u0131lmal\u0131d\u0131r.<\/p>\n

\u25a0 \u015eok diyet, h\u0131zl\u0131 kilo verme ve a\u015f\u0131r\u0131 egzersizden ka\u00e7\u0131n\u0131lmal\u0131d\u0131r.<\/p>\n

\"\"<\/p>\n

\u25a0 A\u015f\u0131r\u0131 hayvansal proteinden uzak durulmal\u0131d\u0131r.<\/p>\n

\u25a0 Alkol t\u00fcketilmemelidir (haftada 3 g\u00fcn bir kadeh \u015farap yeterlidir).<\/p>\n

\u25a0 Bol s\u0131v\u0131 t\u00fcketilmelidir.<\/p>\n

\u25a0 Aspirin ve idrar s\u00f6kt\u00fcr\u00fcc\u00fc i\u00e7eren tansiyon ila\u00e7lar\u0131ndan uzak durulmal\u0131d\u0131r.<\/p>\n

\"\"<\/p>\n

\u25a0 Sebze ve meyve t\u00fcketimi artt\u0131r\u0131lmal\u0131d\u0131r (p\u00fcrinden fakir olanlar).<\/p>\n

\u25a0 Sakatat, a\u015f\u0131r\u0131 k\u0131rm\u0131z\u0131 et, bal\u0131k ve deniz \u00fcr\u00fcnleri, bezelye, mercimek, fasulye, \u0131spanak, mantar ve ku\u015fkonmazdan uzak durulmas\u0131 tavsiye edilir.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u0130\u00e7 Hastal\u0131klar\u0131 Uzman\u0131 Prof. Dr. Osman Erk, \u201c\u00dcrik asit y\u00fcksekli\u011fi; karaci\u011fer ya\u011flanmas\u0131 ve hipertansiyona yol a\u00e7t\u0131\u011f\u0131 gibi kalp damar hastal\u0131klar\u0131 …<\/p>\n","protected":false},"author":1,"featured_media":16915,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[4377,181,4376,1762,1640],"class_list":["post-16914","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-eklem","tag-hastalik","tag-hipertansiyon","tag-meyve","tag-ortaya"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/16914","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=16914"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/16914\/revisions"}],"predecessor-version":[{"id":16916,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/16914\/revisions\/16916"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/16915"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=16914"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=16914"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=16914"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}