G\u00f6rme engelli hastalar, domuz derisi proteininden haz\u0131rlanm\u0131\u015f biyom\u00fchendislik \u00fcr\u00fcn\u00fc bir kornea ald\u0131ktan sonra g\u00f6rme yeteneklerinin bir k\u0131sm\u0131n\u0131 veya tamam\u0131n\u0131 yeniden kazand\u0131lar.<\/b><\/p>\n
\u0130ran ve Hindistan\u2019da ya\u015fayan 20 hastaya, g\u00f6z\u00fcn koruyucu d\u0131\u015f tabakas\u0131n\u0131n giderek inceldi\u011fi ve d\u0131\u015fa do\u011fru \u015fi\u015fti\u011fi keratokonus te\u015fhisi kondu.<\/p>\n
100 bin ki\u015fiden 50 ila 200\u2019\u00fcn\u00fc etkileyen sorun, domuz kolajeniyle geli\u015ftirilen implant sayesinde d\u00fczeltildi. \u0130mplant yerle\u015ftirildikten iki y\u0131l sonra, hastalar\u0131n 14\u2019\u00fc g\u00f6r\u00fc\u015flerinin bir k\u0131sm\u0131n\u0131 veya tamam\u0131n\u0131 yeniden kazand\u0131. \u00dc\u00e7 ki\u015fi ise iyile\u015ftikten sonra m\u00fckemmel g\u00f6r\u00fc\u015fe sahip oldu.<\/p>\n
\u015eimdiye kadar, hastalar\u0131n hi\u00e7birinin v\u00fccudu implant\u0131 reddetmedi, iltihaplanma veya yara izi sorunu ya\u015famad\u0131.<\/p>\n
\u0130sve\u00e7\u2019teki Link\u00f6ping \u00dcniversitesi\u2019ndeki ara\u015ft\u0131rmac\u0131lar taraf\u0131ndan geli\u015ftirilen implant, bir kolajen sol\u00fcsyonunda \u00e7\u00f6z\u00fclm\u00fc\u015f domuz dokusundan yap\u0131ld\u0131. Bu madde, insan korneas\u0131na benzeyen bir hidrojele d\u00f6n\u00fc\u015ft\u00fcr\u00fcld\u00fc. Ard\u0131ndan sentetik kornea, hastalar\u0131n kornealar\u0131na yap\u0131lan bir kesi ile g\u00f6zlerine yerle\u015ftirildi. Ekleme kornealar\u0131 kal\u0131nla\u015ft\u0131rd\u0131 ve \u015feklini geri kazand\u0131rd\u0131.<\/p>\n
VAR OLAN TEDAV\u0130DEN DAHA KOLAY<\/b><\/p>\n
Ara\u015ft\u0131rma ekibi, hastalar\u0131n iyile\u015fmesini g\u00f6zlemledikten iki y\u0131l sonra, Nature Biotechnology dergisinde bulgular\u0131 detayland\u0131rd\u0131.<\/p>\n
Sadece yar\u0131m saat s\u00fcren prosed\u00fcr, genellikle birka\u00e7 saat s\u00fcren geleneksel kornea nakillerinden daha h\u0131zl\u0131 olsa da riskler de ta\u015f\u0131yordu. Yabanc\u0131 bir molek\u00fcl olan kolajenin bir ba\u011f\u0131\u015f\u0131kl\u0131k tepkisi ortaya \u00e7\u0131karma ihtimali oldu\u011fu i\u00e7in ekip, hastalar\u0131 sekiz hafta boyunca imm\u00fcnosupresif g\u00f6z damlalar\u0131 kullanmaya zorlad\u0131.<\/p>\n
Dr Marian Macsai, kornealar\u0131 ihtiya\u00e7 duyabilecek hastalar i\u00e7in daha kolay eri\u015filebilir hale getirebilece\u011fi i\u00e7in yenili\u011fi devrimci olarak niteliyor.<\/p>\n
Kornea k\u00f6rl\u00fc\u011f\u00fc d\u00fcnya \u00e7ap\u0131nda 12 milyon insan\u0131 etkilerken, hastalar\u0131n iyile\u015febilmelerinin tek yolu ise \u00f6len bir don\u00f6r\u00fc beklemek. Oysa domuz derisi kolajeni, g\u0131da end\u00fcstrisinin s\u0131kl\u0131kla at\u0131lan bir yan \u00fcr\u00fcn\u00fc ve bu da onu son derece eri\u015filebilir k\u0131l\u0131yor.<\/p>\n
Ekip, ilerlemeye devam ederken, \u00e7al\u0131\u015fmay\u0131 100\u2019den fazla hastay\u0131 kapsayacak \u015fekilde geni\u015fletmeyi ve ayr\u0131ca yetkililerden implant i\u00e7in d\u00fczenleyici onay almay\u0131 umuyor.<\/p>\n","protected":false},"excerpt":{"rendered":"
G\u00f6rme engelli hastalar, domuz derisi proteininden haz\u0131rlanm\u0131\u015f biyom\u00fchendislik \u00fcr\u00fcn\u00fc bir kornea ald\u0131ktan sonra g\u00f6rme yeteneklerinin bir k\u0131sm\u0131n\u0131 …<\/p>\n","protected":false},"author":1,"featured_media":24119,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[2616,5566,5565],"class_list":["post-24118","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-hastalarin","tag-implant","tag-kornea"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/24118","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24118"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/24118\/revisions"}],"predecessor-version":[{"id":24120,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/24118\/revisions\/24120"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/24119"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24118"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24118"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24118"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}