Uzmanlar, insan yumurtalar\u0131n\u0131n y\u00fczeyinde bulunan yeni bir protein belirlediler. Yunan annelik tanr\u0131\u00e7as\u0131 Maia’dan alan proteinin, sperm ve yumurtalar\u0131n kayna\u015fmas\u0131nda rol oynad\u0131\u011f\u0131 d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/b><\/p>\n
Bilim insanlar\u0131, yeni bir \u00e7al\u0131\u015fmada k\u0131s\u0131rl\u0131\u011fa farkl\u0131 bir yakla\u015f\u0131m sergileyecek bulgular ortaya \u00e7\u0131kard\u0131lar. Ara\u015ft\u0131rmac\u0131lar, insan d\u00f6llenmesinde temel bir ad\u0131m ke\u015ffetti.<\/p>\n
\u00c7al\u0131\u015fman\u0131n ba\u015f ara\u015ft\u0131rmac\u0131s\u0131 olan Sheffield \u00dcniversitesi\u2019nden Prof Harry Moore, bulgular\u0131n bilinmeyen nedenlerle d\u00f6llenmenin ba\u015far\u0131s\u0131z oldu\u011fu vakalara \u0131\u015f\u0131k tutmaya yard\u0131mc\u0131 olabilece\u011fini s\u00f6yledi. Ayr\u0131ca Moore, bir bireyin sperminin Maia\u2019ya ba\u011flan\u0131p ba\u011flanamad\u0131\u011f\u0131n\u0131 veya bir bireyin yumurtalar\u0131n\u0131n y\u00fczeyinde protein olup olmad\u0131\u011f\u0131n\u0131 ara\u015ft\u0131rmak i\u00e7in testlerin geli\u015ftirilebilece\u011fini de belirtti.<\/p>\n
Science Advances dergisinde yazan Birle\u015fik Krall\u0131k, \u00c7ek Cumhuriyeti ve Japonya gibi \u00fclkelerden ara\u015ft\u0131rmac\u0131lar, sentetik mikro boncuklar\u0131n y\u00fczeyine 13 milyon farkl\u0131 protein segmenti veya peptit ekleyerek \u00e7al\u0131\u015fmaya nas\u0131l ba\u015flad\u0131klar\u0131n\u0131 bildirdiler. Her boncuk, bir insan yumurtas\u0131 ile ayn\u0131 boyuttayd\u0131 ve farkl\u0131 bir peptite ba\u011fl\u0131yd\u0131.<\/p>\n
Ekip, bu boncuklarla insan spermini kulu\u00e7kaya yat\u0131rd\u0131\u011f\u0131nda, sperme ba\u011fl\u0131 1000 ki\u015fiden birinden daha az\u0131n\u0131 buldular. Moore, \u201cOnlar\u0131 tan\u0131mlayabilirsiniz, \u00e7\u00fcnk\u00fc sperm, boncuklar\u0131n kendisine ba\u011flan\u0131rken etraf\u0131nda d\u00f6nmesini sa\u011flad\u0131\u201d dedi.<\/p>\n
BA\u011eI\u015eIKLIK S\u0130STEM\u0130N\u0130N B\u0130R B\u0130LE\u015eEN\u0130<\/b><\/p>\n
Ekip, daha fazla \u00e7al\u0131\u015fma yoluyla, bu boncuklar\u0131n y\u00fczeyine ba\u011fl\u0131 olan peptidi ve dolay\u0131s\u0131yla ili\u015fkili oldu\u011fu tam proteini tan\u0131mlayabildi. Ayr\u0131ca v\u00fccuttaki bu \u201cMaia\u201d proteinine yol a\u00e7an geni de tan\u0131mlayabildiler.<\/p>\n
Ekip daha sonra Maia\u2019n\u0131n rol\u00fcn\u00fc incelemek i\u00e7in molek\u00fcler modelleme ve di\u011fer teknikleri kulland\u0131. Yakla\u015f\u0131m, spermin ba\u015flang\u0131\u00e7ta yumurtan\u0131n y\u00fczeyindeki Juno adl\u0131 bir proteine ba\u011fland\u0131\u011f\u0131 \u00f6nceki bulgular\u0131 do\u011frulad\u0131, ancak ayn\u0131 zamanda spermin daha sonra Juno\u2019dan ayr\u0131l\u0131p Maia\u2019ya ba\u011fland\u0131\u011f\u0131n\u0131 da \u00f6nerdi. Maia daha sonra yumurta zar\u0131na \u00e7\u00f6kerek spermi h\u00fccreye \u00e7eker.<\/p>\n
York \u00dcniversitesi\u2019nden Prof Gavin Wright, Maia\u2019n\u0131n daha \u00e7ok ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin bir bile\u015feni oldu\u011fu d\u00fc\u015f\u00fcn\u00fcld\u00fc\u011f\u00fcnde bunun \u015fa\u015f\u0131rt\u0131c\u0131 bir ke\u015fif oldu\u011funu belirtti.<\/p>\n","protected":false},"excerpt":{"rendered":"
Uzmanlar, insan yumurtalar\u0131n\u0131n y\u00fczeyinde bulunan yeni bir protein belirlediler. Yunan annelik tanr\u0131\u00e7as\u0131 Maia’dan alan proteinin, sperm ve …<\/p>\n","protected":false},"author":1,"featured_media":38373,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[500,7483,4945,3169,332],"class_list":["post-38372","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-insan","tag-maia","tag-protein","tag-sperm","tag-yumurta"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/38372","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=38372"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/38372\/revisions"}],"predecessor-version":[{"id":38374,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/38372\/revisions\/38374"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/38373"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=38372"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=38372"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=38372"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}