\u0130ngiliz Daily Mail gazetesi, \u0130ngiltere’de yap\u0131lan yeni bir ara\u015ft\u0131rman\u0131n sonu\u00e7lar\u0131n\u0131 yay\u0131nlad\u0131. Buna g\u00f6re, neden baz\u0131 insanlar\u0131n ‘ak\u015famdan kalma’ s\u00fcrecini daha zor ge\u00e7irdi\u011fi ortaya \u00e7\u0131kar\u0131ld\u0131. <\/b><\/p>\n
\u00c7ok alkol t\u00fcketti\u011finiz bir ak\u015fam\u0131n sabah\u0131nda siz korkun\u00e7 hissederken, yan\u0131n\u0131zda hi\u00e7bir \u015fey yokmu\u015f gibi uyanan arkada\u015flar\u0131n\u0131z vard\u0131r\u2026<\/p>\n
Ak\u015famdan kalma hissetmemeye neden olan \u015feyin asl\u0131nda genetik kaynakl\u0131 oldu\u011fu ortaya \u00e7\u0131kar\u0131ld\u0131. Bug\u00fcne kadar \u2018gece boyu yava\u015f i\u00e7in\u2019, \u2018i\u00e7kiyi suyla i\u00e7in\u2019 gibi ak\u015famdan kalmay\u0131 \u00f6nleyebilece\u011fi \u00f6ne s\u00fcr\u00fclen tezleri \u00e7\u00fcr\u00fcten yeni bir ara\u015ft\u0131rma sonucu yay\u0131nland\u0131.<\/p>\n
Buna g\u00f6re, insanlar\u0131n be\u015fte birinin biyolojik olarak ak\u015famdan kalman\u0131n sonu\u00e7lar\u0131ndan daha az etkilendi\u011fi ortaya \u00e7\u0131kt\u0131. Buna g\u00f6re, insanlar\u0131n be\u015fte birinin, kusma, ba\u015f a\u011fr\u0131s\u0131, mide bulant\u0131s\u0131 gibi semptomlar\u0131n\u0131 di\u011ferlerine oranla daha az ya\u015fad\u0131\u011f\u0131 veya hi\u00e7 ya\u015famad\u0131\u011f\u0131 belirlendi.<\/p>\n
FARKLI GENLER ETK\u0130L\u0130 OLUYOR<\/strong><\/p>\n Ara\u015ft\u0131rmalarda, baz\u0131 ki\u015filerin \u00e7ok fazla alkol t\u00fckettikten sonra kendini k\u00f6t\u00fc hissetmesinin nedenin genlerdeki mutasyonlar oldu\u011fu belirlendi. Uzmanlar, mutasyonlar\u0131n birden \u00fc\u00e7e kadar s\u0131n\u0131fland\u0131r\u0131ld\u0131\u011f\u0131n\u0131 ve bu durumun ki\u015filerin hissetti\u011fi ak\u015famdan kalma semptomlar\u0131n\u0131n ciddiyetini etkileyebilece\u011fini belirtti.<\/p>\n Buna g\u00f6re, CYP2E1 geninin, v\u00fccudun alkol bile\u015fiklerini nas\u0131l par\u00e7alad\u0131\u011f\u0131n\u0131 belirlemekten sorumlu oldu\u011fu ortaya \u00e7\u0131kar\u0131ld\u0131. Buna g\u00f6re, gendeki farkl\u0131l\u0131klar\u0131n v\u00fccudun alkol\u00fc metabolize etme h\u0131z\u0131n\u0131 art\u0131rabilece\u011fi belirlendi.<\/p>\n GENET\u0130K FARKLILIKLAR ETK\u0130L\u0130<\/strong><\/p>\n Ba\u015fka bir gen olan ADH1B\u2019nin de v\u00fccudun alkol\u00fc asetaldehit ad\u0131 verilen bir maddeye nas\u0131l d\u00f6n\u00fc\u015ft\u00fcrd\u00fc\u011f\u00fcn\u00fc d\u00fczenledi\u011fi belirlendi. Asetaldehit, karaci\u011ferde birikerek ak\u015famdan kalma hissine neden olan ve sonu\u00e7 olarak ili\u015fkili ba\u015f a\u011fr\u0131lar\u0131na ve mide bulant\u0131s\u0131na neden olan organik bir kimyasald\u0131r. Ayr\u0131ca, bir ki\u015finin v\u00fccudunda uzun vadeli hasara neden oldu\u011fu ve hatta kronik hastal\u0131k ve organ sorunlar\u0131 riski olu\u015fturdu\u011fu bilinmektedir.<\/p>\n Baz\u0131 insanlar bu semptomlar\u0131 ya\u015famazlar veya ya\u015fasalar da pek etkilenmezler. Ara\u015ft\u0131rmalara g\u00f6re bunun nedeni ise v\u00fccutlar\u0131n\u0131n alkol\u00fc nas\u0131l i\u015fledi\u011fini ve metabolize etti\u011fini etkileyen genetik farkl\u0131l\u0131klar olabilir.<\/p>\n KADIN VE ERKEKLERDE FARKLILIK G\u00d6STER\u0130YOR<\/strong><\/p>\n Daha \u00f6nce 2014 y\u0131l\u0131nda yap\u0131lan bir ara\u015ft\u0131rma, erkeklerde ak\u015famdan kalma s\u0131kl\u0131\u011f\u0131n\u0131 y\u00fczde 45 olarak belirlerken bu oran kad\u0131nlarda y\u00fczde 40 olarak a\u00e7\u0131klanm\u0131\u015ft\u0131.<\/p>\n Uzmanlar, genetik fakt\u00f6rlerin ki\u015filerin ak\u015famdan kalma olma durumunu y\u00fczde 43 olarak etkiledi\u011fini belirlerken, gerisinin muhtemelen bir ki\u015finin ne kadar h\u0131zl\u0131 i\u00e7ti\u011fi veya i\u00e7erken yiyip yemedi\u011fi gibi d\u0131\u015f fakt\u00f6rlerden kaynakland\u0131\u011f\u0131 ifade edildi.<\/p>\n","protected":false},"excerpt":{"rendered":" \u0130ngiliz Daily Mail gazetesi, \u0130ngiltere’de yap\u0131lan yeni bir ara\u015ft\u0131rman\u0131n sonu\u00e7lar\u0131n\u0131 yay\u0131nlad\u0131. Buna g\u00f6re, neden baz\u0131 insanlar\u0131n ‘ak\u015famdan kalma …<\/p>\n","protected":false},"author":1,"featured_media":46571,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[8559,954,2153,295,378],"class_list":["post-46570","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-aksamdan-kalma","tag-alkol","tag-farkli","tag-gen","tag-neden"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/46570","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=46570"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/46570\/revisions"}],"predecessor-version":[{"id":46572,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/46570\/revisions\/46572"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/46571"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=46570"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=46570"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=46570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}