ABD merkezli ila\u00e7 \u015firketi Moderna, corona vir\u00fcs\u00fc a\u015f\u0131lar\u0131nda da kullan\u0131lan mRNA teknolojisini kullanarak kanserli h\u00fccreleri yok etmeyi ba\u015fard\u0131\u011f\u0131n\u0131 duyurdu.<\/p>\n
ABD merkezli \u015firket taraf\u0131ndan yap\u0131lan a\u00e7\u0131klamada a\u015f\u0131n\u0131n cilt kanserine sebep olan melanoma kar\u015f\u0131 etkili sonu\u00e7lar ortaya \u00e7\u0131kard\u0131\u011f\u0131 belirtildi. Moderna\u2019n\u0131n a\u015f\u0131s\u0131 ile birlikte Merck\u2019in geli\u015ftirdi\u011fi Keytruda isimli ilac\u0131n birlikte kullan\u0131lmas\u0131 durumunda \u00f6l\u00fcmc\u00fcl cilt kanserinde \u00f6l\u00fcm ya da hastal\u0131\u011f\u0131n yeniden ortaya \u00e7\u0131kmas\u0131 riskini sadece Keytruda kullan\u0131lmas\u0131 durumuna oranla y\u00fczde 44 oran\u0131nda azaltt\u0131\u011f\u0131 a\u00e7\u0131kland\u0131.<\/p>\n
H\u0130SSELER FIRLADI<\/strong><\/p>\n \u015eirketler taraf\u0131ndan yap\u0131lan a\u00e7\u0131klamada, \u201cBu sonu\u00e7 istatistiksel olarak \u00f6nemli ve klinik olarak \u00e7ok anlaml\u0131 bir geli\u015fme\u201d denildi. Verilerin payla\u015f\u0131lmas\u0131 sonras\u0131nda Moderna\u2019n\u0131n hisseleri artarken mRNA bazl\u0131 a\u015f\u0131 \u00e7al\u0131\u015fmalar\u0131 y\u00fcr\u00fcten T\u00fcrk bilim insanlar\u0131 \u00d6zlem T\u00fcreci ve U\u011fur \u015eahin\u2019in \u015firketi BioNTech\u2019in hisseleri y\u00fckseli\u015f trendine girdi.<\/p>\n Bu ara\u015ft\u0131rman\u0131n mRNA a\u015f\u0131 teknolojisi ile ila\u00e7lar\u0131n birlikte kullan\u0131m\u0131n\u0131n ba\u011f\u0131\u015f\u0131kl\u0131\u011fa nas\u0131l etki edece\u011fini g\u00f6steren ilk ara\u015ft\u0131rma olarak kay\u0131tlara ge\u00e7erken, teknik olarak bu y\u00f6ntemin di\u011fer kanser t\u00fcrlerine de etkisi oldu\u011funu aktard\u0131.<\/p>\n YAN ETK\u0130 R\u0130SK\u0130 Y\u00dcZDE 14.4<\/strong><\/p>\n Moderna\u2019n\u0131n t\u0131bbi geli\u015fmelerden sorumlu genel m\u00fcd\u00fcr yard\u0131mc\u0131s\u0131 Paul Burton da, \u201cBu ara\u015ft\u0131rma sonu\u00e7lar\u0131 kanserin tedavisinde yeni bir bak\u0131\u015f a\u00e7\u0131s\u0131 sa\u011flayacak\u201d dedi.<\/p>\n \u00dc\u00e7\u00fcnc\u00fc ve d\u00f6rd\u00fcnc\u00fc evredeki 157 cilt kanseri hastas\u0131n\u0131 inceleyen bilim insanlar\u0131 sadece Keytruda kullan\u0131lan durumlarla hem mRNA bazl\u0131 a\u015f\u0131 hem de Keytruda kullan\u0131lan durumlar\u0131 k\u0131yaslad\u0131. Her iki ilac\u0131n kullan\u0131ld\u0131\u011f\u0131 durumlarda yan etki g\u00f6r\u00fclmesi durumu y\u00fczde 14.4 olarak kay\u0131tlara ge\u00e7erken sadece Keytruda kullan\u0131m\u0131nda ise yan etki g\u00f6r\u00fclme oran\u0131n\u0131n ise y\u00fczde 10 seviyelerinde oldu\u011fu belirtildi.<\/p>\n A\u015eI NASIL \u00c7ALI\u015eIYOR?<\/strong><\/p>\n Ki\u015fiye \u00f6zel olarak geli\u015ftirilebilecek a\u015f\u0131 i\u00e7in hastadan t\u00fcm\u00f6r \u00f6rne\u011fi ve sa\u011fl\u0131kl\u0131 doku \u00f6rne\u011fi al\u0131yor. Daha sonra uzmanlar gen dizilimini, mutasyona u\u011frayan proteinleri ve di\u011fer verileri inceleyerek ki\u015fiye \u00f6zel bir kanser a\u015f\u0131s\u0131 geli\u015ftiriyor. Bu kar\u0131\u015f\u0131m hastaya enjekte edildi\u011finde hastan\u0131n h\u00fccreleri bir \u00fcretim merkezi gibi \u00e7al\u0131\u015farak bunun kopyalar\u0131n\u0131 \u00fcretiyor ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemi t\u00fcm\u00f6r\u00fc fark edip yok edebiliyor.<\/p>\n Moderna, ki\u015fiye \u00f6zel bir a\u015f\u0131n\u0131n 8 haftal\u0131k bir s\u00fcrede \u00fcretilebildi\u011fini de belirtti.<\/p>\n ARA\u015eTIRMA HEN\u00dcZ \u0130NCELENMED\u0130<\/strong><\/p>\n Fakat baz\u0131 uzmanlar bu ara\u015ft\u0131rman\u0131n hen\u00fcz \u00e7ok ufak bir b\u00f6l\u00fcm\u00fcn\u00fcn kamuoyu ile payla\u015f\u0131ld\u0131\u011f\u0131n\u0131 a\u00e7\u0131klad\u0131.<\/p>\n \u0130ngiliz Financial Times gazetesine konu\u015fan uzmanlar bu ara\u015ft\u0131rma sonu\u00e7lar\u0131n\u0131n hen\u00fcz hakemli bir dergide yay\u0131nlanmad\u0131\u011f\u0131na da dikkat \u00e7ekti.<\/p>\n","protected":false},"excerpt":{"rendered":" Covid-19 ile birlikte hayat\u0131m\u0131za giren mRNA a\u015f\u0131lar ile ilgili yeni geli\u015fmeler t\u0131p d\u00fcnyas\u0131nda yeni bir umut oldu.<\/p>\n","protected":false},"author":1,"featured_media":62480,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[226,180,3255,1934],"class_list":["post-62479","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-arastirma","tag-asi","tag-etki","tag-kanser"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/62479","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=62479"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/62479\/revisions"}],"predecessor-version":[{"id":62481,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/62479\/revisions\/62481"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/62480"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=62479"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=62479"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=62479"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}