Merkezi Hong Kong’da bulunan Insilico Medicine, ISM3312 terap\u00f6tik \u00fcr\u00fcn\u00fcn\u00fcn, klinik denemeler \u00f6ncesi \u00e7al\u0131\u015fmalar\u0131nda akci\u011ferlerdeki viral y\u00fck\u00fc ve iltihab\u0131 \u201c\u00f6nemli \u00f6l\u00e7\u00fcde azaltt\u0131\u011f\u0131n\u0131n\u201d saptand\u0131\u011f\u0131n\u0131 bildirdi.<\/p>\n
Kanadal\u0131 bilim insan\u0131 Dr. Alex Zhavoronkov yapt\u0131\u011f\u0131 a\u00e7\u0131klamada kurucusu ve \u00fcst y\u00f6neticisi oldu\u011fu \u015firketin ila\u00e7 konusunda yapay zeka ile \u00e7al\u0131\u015fmalar yapt\u0131\u011f\u0131n\u0131 belirterek, \u201c\u00dcretken yapay zeka, insan geli\u015fiminin her alan\u0131n\u0131 d\u00f6n\u00fc\u015ft\u00fcr\u00fcyor. \u00dcretken yapay zeka kullan\u0131larak \u00fcretilen ikinci k\u00fc\u00e7\u00fck molek\u00fcl terap\u00f6tik ilac\u0131m\u0131z\u0131n art\u0131k insan klinik denemelerine girdi\u011fini, ke\u015fif ve geli\u015ftirme d\u00f6ng\u00fcs\u00fcn\u00fc g\u00f6stermek i\u00e7in \u00e7ok net bir zaman \u00e7izelgesinde oldu\u011funu duyurmaktan son derece mutluyuz.\u201d dedi.<\/p>\n
Zhavoronkov, \u015fimdiye kadar ilk kez yapay zeka ile tasarlanm\u0131\u015f bir Covid-19 ilac\u0131n\u0131n klinik denemelerine ba\u015fland\u0131\u011f\u0131na i\u015faret ederek, ISM3312 terap\u00f6tik \u00fcr\u00fcn\u00fcn\u00fcn, insanlar \u00fczerindeki klinik denemelerinin \u00c7in\u2019de ba\u015flayaca\u011f\u0131n\u0131 bildirdi.<\/p>\n
\u015eirketten yap\u0131lan a\u00e7\u0131klamada da ilac\u0131n, vir\u00fcsteki proteazlar olarak bilinen enzimleri geri d\u00f6n\u00fc\u015f\u00fcms\u00fcz ba\u011flay\u0131p inhibe ederek \u00e7al\u0131\u015ft\u0131\u011f\u0131 ve hedefledi\u011fi proteaz\u0131n da SARS-CoV-2 vir\u00fcs\u00fcnde bulunan ana proteaz olan 3CLpro olarak adland\u0131r\u0131ld\u0131\u011f\u0131 belirtildi.<\/p>\n
A\u00e7\u0131klamada ISM3312\u2019nin hedefledi\u011fine benzer proteazlar\u0131n t\u00fcm corona vir\u00fcslerde bulundu\u011fu, bunun da ilac\u0131n yaln\u0131zca SARS-CoV-2\u2019nin mevcut ve gelecekteki varyantlar\u0131n\u0131 de\u011fil, di\u011fer corona vir\u00fcsleri de hedeflemede etkili olabilece\u011fi anlam\u0131na geldi\u011fi ifade edildi.<\/p>\n","protected":false},"excerpt":{"rendered":"
Yapay zeka ile tasarlan\u0131p geli\u015ftirilen ilk yeni tip corona vir\u00fcs\u00fc (Covid-19) ilac\u0131n\u0131n insanlar \u00fczerindeki klinik denemelerine ba\u015fland\u0131\u011f\u0131 duyuruldu.<\/p>\n","protected":false},"author":1,"featured_media":72706,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[],"class_list":["post-72705","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/72705","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=72705"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/72705\/revisions"}],"predecessor-version":[{"id":72707,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/72705\/revisions\/72707"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/72706"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=72705"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=72705"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=72705"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}