Dailymail\u2019in haberine g\u00f6re, New York \u00dcniversitesi Grossman T\u0131p Okulundan bir grup ara\u015ft\u0131rmac\u0131, farelerdeki ya\u015flanman\u0131n belirtisi olan beyaz t\u00fcyleri inceledikleri s\u0131rada, bir\u00e7ok farkl\u0131 h\u00fccre tipine d\u00f6n\u00fc\u015febilen k\u00f6k h\u00fccrelerin, k\u0131l k\u00f6klerindeki geli\u015fim b\u00f6l\u00fcmleri aras\u0131nda hareket etme yetene\u011fine sahip oldu\u011funu ke\u015ffetti.<\/p>\n
Bunun ard\u0131ndan ara\u015ft\u0131rmac\u0131lar, insanlarda da bulunan ve sa\u00e7 rengini kontrol eden melanosit k\u00f6k h\u00fccrelerine odakland\u0131.<\/p>\n
S\u0131k\u0131\u015fm\u0131\u015f k\u00f6k h\u00fccreli k\u0131l k\u00f6kleri, normal sa\u00e7larda y\u00fczde 15 oran\u0131ndayken, ayn\u0131 denekteki y\u0131pranm\u0131\u015f ve eski sa\u00e7larda bu oran\u0131n daha y\u00fcksek oldu\u011fu tespit edildi.<\/p>\n
Bu bilgiden yola \u00e7\u0131karak, s\u0131k\u0131\u015fm\u0131\u015f h\u00fccrelerin, geli\u015fmekte olan k\u0131l k\u00f6k\u00fc (folik\u00fclit) b\u00f6lmeleri aras\u0131nda tekrar hareket etmesine yard\u0131mc\u0131 olman\u0131n, insan sa\u00e7\u0131n\u0131n beyazlamas\u0131n\u0131 tersine \u00e7evirmek veya \u00f6nlemek i\u00e7in potansiyel bir yol sunabilece\u011fi sonucuna var\u0131ld\u0131.<\/p>\n
\u00c7al\u0131\u015fman\u0131n ba\u015f ara\u015ft\u0131rmac\u0131s\u0131 Qi Sun, a\u00e7\u0131klamas\u0131nda, \u201c\u00c7al\u0131\u015fmam\u0131z, melanosit k\u00f6k h\u00fccrelerinin sa\u00e7\u0131 renklendirmek i\u00e7in nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131na dair temel anlay\u0131\u015f\u0131m\u0131za katk\u0131da bulunuyor.\u201d dedi.<\/p>\n
Ara\u015ft\u0131rma ekibi, \u015fimdi ise k\u00f6k h\u00fccrelere hareketlili\u011fi geri kazand\u0131rman\u0131n veya onlar\u0131 pigment \u00fcretebilecekleri ve t\u00fcylerin grile\u015fmesini durdurabilecekleri b\u00f6lmeler aras\u0131nda fiziksel olarak hareket ettirmenin potansiyel yollar\u0131n\u0131 ara\u015ft\u0131rmay\u0131 planlad\u0131klar\u0131n\u0131 aktard\u0131.<\/p>\n
K\u0131demli ara\u015ft\u0131rmac\u0131 Mayumi Uti, sa\u00e7 renginin beyazlamas\u0131 ve sa\u00e7 kayb\u0131ndan sorumlu olabilecek \u015feyin, melanosit k\u00f6k h\u00fccrelerinde renk de\u011fi\u015fimine neden olan i\u015flev kayb\u0131 olabilece\u011fini kaydetti.<\/p>\n
Uti, elde ettikleri bulgular\u0131n, melanosit k\u00f6k h\u00fccre hareketlili\u011finin sa\u011flanmas\u0131n\u0131n, sa\u00e7\u0131 sa\u011fl\u0131kl\u0131 ve renkli tutman\u0131n anahtar\u0131 oldu\u011funu g\u00f6sterdi\u011fini s\u00f6yledi.<\/p>\n
Ya\u015fland\u0131k\u00e7a sa\u00e7larda meydana gelen d\u00f6k\u00fclme ve tekrar uzama d\u00f6ng\u00fcs\u00fcn\u00fcn, bu k\u00f6k say\u0131s\u0131n\u0131n artarak s\u0131k\u0131\u015fmas\u0131na neden oldu\u011fu, bunun da sa\u00e7 k\u00f6klerinin protein almas\u0131na engel olarak pigment h\u00fccrelerine d\u00f6n\u00fc\u015fmelerini engelledi\u011fi biliniyor. Gen\u00e7likte ise bu h\u00fccrelerin geli\u015fmekte olan k\u0131l k\u00f6k\u00fc b\u00f6lmeleri aras\u0131nda hareket etti\u011fi ve farkl\u0131 seviyelerde proteinlere maruz kald\u0131\u011f\u0131 ifade ediliyor. (AA)<\/p>\n","protected":false},"excerpt":{"rendered":"
Ara\u015ft\u0131rmac\u0131lar, ya\u015flanman\u0131n en \u00f6nemli belirtilerinden olan sa\u00e7lar\u0131n beyazlamas\u0131n\u0131 tersine \u00e7evirmenin veya \u00f6nlemenin yolunu bulmaya bir ad\u0131m daha yakla\u015ft\u0131.<\/p>\n","protected":false},"author":1,"featured_media":77763,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[29],"tags":[226,4446,4100,5548,4078],"class_list":["post-77762","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-magazin","tag-arastirma","tag-hareket","tag-kok","tag-kok-hucre","tag-sac"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/77762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=77762"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/77762\/revisions"}],"predecessor-version":[{"id":77764,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/77762\/revisions\/77764"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/77763"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=77762"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=77762"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=77762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}