{"id":82712,"date":"2023-04-28T14:39:03","date_gmt":"2023-04-28T14:39:03","guid":{"rendered":"https:\/\/haberulus.net\/?p=82712"},"modified":"2023-04-28T14:39:03","modified_gmt":"2023-04-28T14:39:03","slug":"bilimsel-arastirma-uzun-yasamanin-formulu-bulundu","status":"publish","type":"post","link":"https:\/\/haberulus.net\/?p=82712","title":{"rendered":"Bilimsel ara\u015ft\u0131rma: Uzun ya\u015faman\u0131n form\u00fcl\u00fc bulundu"},"content":{"rendered":"

ABD\u2019deki California San Diego \u00dcniversitesi\u2019nden bir ara\u015ft\u0131rma ekibinin, biyolojik saati nas\u0131l yeniden d\u00fczenleyip, bir bulu\u015f olabilecek \u015fekilde \u00e7\u00f6zm\u00fc\u015f olabilece\u011fi iddia edildi.<\/p>\n

<\/span><\/span>Maya h\u00fccrelerinin \u00f6mr\u00fcn\u00fc y\u00fczde 80\u2019den fazla art\u0131rabilen ara\u015ft\u0131rmac\u0131lar, ayn\u0131 \u015feyin daha karma\u015f\u0131k insan h\u00fccrelerinde de yap\u0131labilece\u011fini savundular.\u00a0<\/span><\/p>\n

Ya\u015flanman\u0131n tedavi edilebilen bir hastal\u0131k oldu\u011funa inanan ara\u015ft\u0131rmac\u0131lar,\u00a0<\/span>\u201c\u00c7al\u0131\u015fmam\u0131z, h\u00fccresel ya\u015flanma s\u00fcrecini yeniden programlamak i\u00e7in sentetik biyolojinin ba\u015far\u0131l\u0131 bir \u015fekilde uyguland\u0131\u011f\u0131n\u0131 g\u00f6steren bir kavram\u0131 temsil ediyor ve daha karma\u015f\u0131k organizmalarda uzun \u00f6m\u00fcrl\u00fcl\u00fc\u011f\u00fc etkili bir \u015fekilde te\u015fvik etmek i\u00e7in sentetik genleri tasarlaman\u0131n temelini olu\u015fturabilir.\u201d diye yazd\u0131.<\/span><\/p>\n

DAHA FAZLA ARA\u015eTIRMAYA \u0130HT\u0130YA\u00c7 VAR<\/b><\/p>\n

Ara\u015ft\u0131rmac\u0131lar, \u00e7al\u0131\u015fmalar\u0131n\u0131, \u201c\u0130nsan h\u00fccreleri, v\u00fccudumuzun ya\u015famak i\u00e7in ihtiya\u00e7 duydu\u011fu t\u00fcm \u00f6nemli s\u00fcre\u00e7leri ger\u00e7ekle\u015ftiren mini fabrikalar gibi \u00e7al\u0131\u015f\u0131r. <\/span>Sorun \u015fu ki, bu kimyasal reaksiyonlar, biz ya\u015fland\u0131k\u00e7a kademeli olarak biriken ve DNA\u2019m\u0131zla di\u011fer h\u00fccresel bile\u015fenlere zarar veren zehirli at\u0131k \u00fcr\u00fcnler \u00fcretebilir. <\/span>Bu nedenle, v\u00fccudumuz herhangi bir hasara yol a\u00e7madan \u00f6nce bu h\u00fccreleri kapatmak i\u00e7in yeni y\u00f6ntemler bulundu.\u201d s\u00f6zleriyle \u00e7al\u0131\u015fmalar\u0131n\u0131 \u00f6zetledi.<\/span><\/p>\n

Per\u015fembe g\u00fcn\u00fc Science dergisinde yay\u0131nlanan UC San Diego \u00e7al\u0131\u015fmas\u0131nda ekip, ya\u015flanma s\u00fcreci i\u00e7in bir model olarak maya h\u00fccrelerini kulland\u0131.\u00a0<\/span>Bunun nedeni, maya h\u00fccrelerindeki do\u011fal genetik devrelerin, onlar\u0131n insan h\u00fccrelerine benzer bir \u015fekilde ya\u015fa ba\u011fl\u0131 kalmalar\u0131 oldu.
<\/span><\/p>\n

Ara\u015ft\u0131rmac\u0131lar, h\u00fccrelerin iki ya\u015flanma mekanizmas\u0131 aras\u0131nda d\u00fczenli olarak de\u011fi\u015f toku\u015f yapmas\u0131na izin veren ve normal h\u0131zda ya\u015flanmalar\u0131n\u0131 \u00f6nleyen yeni bir genetik devre yaratt\u0131.\u00a0<\/span>Bu h\u00fccreler, hi\u00e7 dokunulmayanlardan y\u00fczde 82 daha uzun ya\u015fad\u0131.<\/span><\/p>\n

Ekip, ara\u015ft\u0131rmalar\u0131n\u0131 k\u00f6k h\u00fccreler ve n\u00f6ronlar gibi farkl\u0131 insan h\u00fccresi t\u00fcrleri \u00fczerinde tekrarlamak istiyor. Buna g\u00f6re s<\/span>onsuza kadar ya\u015famak m\u00fcmk\u00fcn olmasa da, bilim insanlar\u0131 insanlar\u0131n \u00f6mr\u00fcn\u00fc ciddi oranda uzatabilir.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Yap\u0131lan yeni bir \u00e7al\u0131\u015fmaya g\u00f6re, ABD’li bilim insanlar\u0131, h\u00fccrelerin ya\u015fam s\u00fcrelerini tam y\u00fczde 80 oran\u0131nda art\u0131rman\u0131n form\u00fcl\u00fc bulmu\u015f olabilir.<\/p>\n","protected":false},"author":1,"featured_media":82713,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[226,500,11362],"class_list":["post-82712","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-arastirma","tag-insan","tag-yaslanma"],"_links":{"self":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/82712","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=82712"}],"version-history":[{"count":1,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/82712\/revisions"}],"predecessor-version":[{"id":82714,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/posts\/82712\/revisions\/82714"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=\/wp\/v2\/media\/82713"}],"wp:attachment":[{"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=82712"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=82712"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haberulus.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=82712"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}